LifeStar Response Corporation of Maryland was established in 1998 through the consolidation of Advanced Care , Huntemann Ambulance and Maryland Ambulance services.

After many years of providing excellent customer service, LifeStar Response grew to be the premier provider in the Mid-Atlantic area. In 2006 LifeStar Response made another acquisition of Best American Ambulance followed up by a 2009 acquisition of AmeriCare, then in 2011 Lifestar Ambulance was acquired to solidify Lifestar's position as the largest private ambulance service in Maryland.

Locally, LifeStar Response provides a full range of medical transportation services to residents of Central Maryland, Metropolitan Washington, Central Delaware and Northern Virginia. Nationally, LifeStar serves communities in Alabama, Georgia, New Jersey and New York.